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D-mannose is a naturally occurring hexose sugar, presented as a white crystalline, water-soluble powder, and commonly found in fruits like cranberries, oranges, and apples. It plays a vital role in glycoprotein synthesis and cellular signaling, making it valuable across various health and wellness applications. In healthcare, D-mannose is best known for preventing UTIs by blocking bacterial adhesion and supporting kidney and immune health. In the food and beverage industry, it serves as both a nutritional supplement and flavor enhancer. Additionally, it offers moisturizing and skin-repairing benefits in cosmetic formulations.
Key Properties:
- A monosaccharide (hexose sugar), white crystalline powder, water-soluble.
- Naturally found in cranberries, oranges, apples, and certain plants.
- Participates in glycoprotein synthesis and cellular signaling.
Applications:
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Healthcare
- Prevents urinary tract infections (UTIs) by inhibiting bacterial adhesion.
- Supports kidney health and immune function.
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Food & Beverage
- Nutritional supplement for energy and metabolic health.
- Flavor enhancer in functional foods.
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Cosmetics
- Moisturizing agent in skincare products.
- Promotes wound healing and skin repair.
| CAS Number | Specifications | Characteristic | Main Applications |
|
3458-28-4 |
99% |
White powder |
Food, medicine, cosmetics, feed, industry |
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I. Europe & Americas: Food-Grade Low-Sugar Functional Ingredient
Product Case: Nature's Answer (USA) · UT Answer Cranberry D-Mannose Oral Liquid
Nature’s Answer, a botanical extract brand and a benchmark in functional beverages, developed a bestselling urinary tract health oral liquid using D-Mannose, cranberry juice, and vitamin C for the U.S. market.
Core Value of D-Mannose
- 4,370mg D-Mannose per 120ml (3.6% of finished product)
- Combined with cranberry juice and vitamin C.
- Low-sugar and natural formula for urinary tract health
- No artificial additives
- Compliant with FDA filing, GMP and USDA Organic certification
Market Performance
Top-selling product in the U.S. urinary tract health beverage segment, long-term bestseller on Amazon, and high repurchase rate. Riding the North American urinary tract health supplement market with 6.5% annual growth, it has become a mainstream choice for natural health demand.
Cooperation Confidence
- Adopted by leading U.S. functional beverage brands
- Mature dosage and formulation logic for market launch
- FDA, GMP, and Organic-compliant supply chain
Product Description
Food additive and dietary supplement raw material, suitable for low-sugar food and dietary supplement processing. Food-grade 99% D-Mannose is suitable for low-sugar food processing and dietary supplement manufacturing.
It complies with FDA GRAS and EU E421 food additive standards while supporting gluten-free and non-GMO product development. Packaged in 25kg food-grade kraft paper bags with PE inner lining, each batch includes COA testing for purity, heavy metals, and microbial indicators under ISO 22000 food safety standards.
FAQ
What specific food categories can it be used in?
In line with European and American food additive standards, it can be used in hard candies (5%–20%), sugar-free beverages (0.1%–1%), baked goods (1%–3%) and dietary supplements (daily dose ≤3g). We provide dosage reference for different food matrices.
Are additional certifications required for export to the EU?
Registered with EU REACH (E421 code) and FSSC 22000 certified. Packaging is labeled for dual use as "food additive" and "dietary supplement raw material" to avoid medical claims, directly cleared for 27 EU countries.
Is it suitable for diabetic foods?
Yes. The metabolic rate of D-mannose is only 1/20 of glucose, with no impact on blood sugar fluctuation. It can be used as a sugar substitute for sugar-free foods. Labeling shall state "suitable for diabetics" and maximum daily intake ≤3g.
II. Middle East: Halal Food-Grade Functional Ingredient
Product Case: Al Nassma (UAE) · Camel Milk Chocolate Series
A brand exclusively supplied to the Dubai Royal Family, the world’s first camel milk chocolate brand, and a benchmark for high-end chocolate in the Middle East. Al Nassma uses D-Mannose in premium camel milk chocolate formulations, proving its high-end application value in the Middle East and building strong confidence for partners.
Core Value of D-Mannose
- Halal-certified ingredient suitable for Middle Eastern food production
- Dosage 3%–5%, replacing part of sucrose in low-sugar formulations
- Compatible with camel milk, cocoa, and traditional ingredients
- No artificial additives or preservatives
- Suitable for beverages, candies, pastries, and specialty drinks
Market Performance
Top-selling high-end chocolate in the Middle East, covering GCC core countries (UAE, Saudi Arabia, etc.) and exported to Europe, Hong Kong and other markets. Riding the Middle Eastern chocolate market of $1.23 billion, it is the preferred gift for royal banquets and high-end social occasions.
Cooperation Confidence
- High-End Validation: Verified by premium Middle Eastern food brands
- Low Trial & Error: Supports Halal-compliant and low-sugar formulations
- Full Compliance: Stable export-ready supply chain with international certifications
Product Description
Food-grade D-Mannose with Halal certification is suitable for sugar-free foods and traditional beverage processing throughout Middle Eastern markets. Its 99% purity plant-derived formula complies with Islamic dietary requirements and supports low-sugar product development.
Packaged in 25kg food-grade aluminum foil bags with moisture-proof protection, the product supports Arabic label customization and includes Saudi SFDA Halal certification for export and regional food processing compliance.
FAQ
How to verify the Halal certification?
Certified by the Islamic Food and Nutrition Council of America (IFANCA), verifiable on the Saudi SFDA official website by entering the certification number. 100% plant-derived raw materials, no cross-contamination of animal ingredients during production.
What is the recommended dosage in Middle Eastern food?
0.5%–1% in Ramadan drinks, 3%–8% in candies, 1%–5% in baked goods. It can replace part of sucrose to reduce calories without affecting the original flavor.
Can storage conditions adapt to high temperatures in the Middle East?
Sealed storage in a dry place at room temperature (≤35℃), 2-year shelf life. Avoid direct sunlight in high-temperature environments; use within 3 months after opening. Caking does not affect edible quality.
III. Asia: Food-Grade Universal Functional Ingredient
Product Case
Pan Pan Food (Top 3 in China’s baking industry, annual revenue exceeding 10 billion RMB), uses D-Mannose in low GI sugar-free whole wheat biscuits, supporting large-scale healthy snack production in China.
Core Value of D-Mannose
- 99% high-purity crystalline D-mannose
- Dosage 2%–3% of flour (1.5%–2% of finished product)
- Supports low GI and sugar-free food formulations
- Combined with erythritol and whole wheat flour to achieve GI ≤49
- Fast dissolution and stable bulk density
- Suitable for snacks, beverages, and supplement products
Market Performance
It was an instant bestseller, over 2 million bags sold online, covering national chain supermarkets offline, with a repurchase rate 41.8% (far above the industry average), becoming a mainstream choice for glycemic control and weight management groups.
Cooperation Confidence
- Long-term procurement by Pan Pan Food, proving D-mannose is a bestseller standard ingredient for healthy food.
- Mature dosage guidance for low-sugar food launch
- Export-ready production supporting Asian regulatory standards
Product Description
Food-grade D-Mannose complies with China GB 1886.177 standards and supports dietary supplement, snack food, and beverage processing across Asian markets. Its 99% purity plant fermentation process ensures stable quality and reliable industrial performance.
Produced under GB 14881 production standards, the product includes Chinese-English COA reports and supports customized particle sizes and small-pack sample options for regional manufacturing and export applications.
FAQ
What certifications are required for export to Southeast Asia?
Certified by Singapore SFA and Malaysia NPDA for food raw materials. Default Chinese-English labels, with optional Thai/Indonesian labels, are directly cleared for ASEAN countries without additional registration.
What Asian specialty foods can it be used in?
Japanese and Korean low-sugar snacks (3%–8%), Chinese compressed tablets (5%–10%), Southeast Asian herbal teas (0.3%–1%), and Taiwan enzyme products (1%–3%). We provide targeted formula adaptation suggestions.
What compliant claims are allowed as a food raw material?
Labelable as "natural sweetener", "low glycemic index", "helps regulate intestinal health". Medical claims are prohibited, compliant with China GB 2760 and Asian national food safety regulations.